Dosimetry for audit and clinical trials: challenges and requirements

Dosimetry for audit and clinical trials: challenges and requirements

Many important dosimetry audit networks for radiotherapy have their roots in clinical trial quality assurance (QA). In both scenarios it is essential to test two issues: does the treatment plan conform with the clinical requirements and is the plan a reasonable representation of what is actually delivered to a patient throughout their course of treatment. Part of a sound quality program would b...

Clinical decision supports for brain-dead kidney allocation: a review study of requirements, challenges, and solutions

Introduction: With the change in the epidemiology of diseases, chronic kidney disease has shown a significant increase worldwide. Kidney transplantation is the optimal treatment option to improve patient quality of life. The main challenge in benefiting from a brain-dead patient's kidney is the selection of a right recipient in limited time. The purpose of this study was to review the requireme...

Clinical decision supports for brain-dead kidney allocation: a review study of requirements, challenges, and solutions

Introduction: With the change in the epidemiology of diseases, chronic kidney disease has shown a significant increase worldwide. Kidney transplantation is the optimal treatment option to improve patient quality of life. The main challenge in benefiting from a brain-dead patient's kidney is the selection of a right recipient in limited time. The purpose of this study was to review the requireme...

Academically led clinical trials: challenges and opportunities

Academically led clinical trials: challenges and opportunities Highlights from ASCO 2015 demonstrate the impasse we face in solid tumour oncology: the compelling novel immune and targeted therapies are often associated with cost–benefit ratios significantly above the thresholds for reimbursement. This is at least in part a consequence of our incomplete understanding of the mechanisms of respons...

Clinical Trials in Glioblastoma — Designs and Challenges